Cell surface expression of 78-kDa glucose-regulated protein (GRP78) mediates diabetic nephropathy

The 78-kDa glucose-regulated protein (GRP78) is a well-established endoplasmic reticulum (ER)-resident chaperone that maintains protein homeostasis and regulates the unfolded protein response. Under conditions of ER stress, GRP78 is also expressed at the cell surface and implicated in tumorigenesis,...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Van Krieken, Richard, Mehta, Neel, Wang, Tony, Zheng, Mengyu, Li, Renzhong, Gao, Bo, Ayaub, Ehab, Ask, Kjetil, Paton, James C., Paton, Adrienne W., Austin, Richard C., Krepinsky, Joan C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6514638/
https://ncbi.nlm.nih.gov/pubmed/30914477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006939
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