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Targeting GRP78 to enhance melanoma cell death
Targeting endoplasmic-reticulum (ER) stress-induced apoptosis may offer an alternative therapeutic strategy for metastatic melanoma. Fenretinide and bortezomib induce apoptosis of melanoma cells but their efficacy may be hindered by the unfolded protein response (UPR) which promotes survival by amel...
में बचाया:
| मुख्य लेखकों: | , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2941718/ https://ncbi.nlm.nih.gov/pubmed/20546536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2010.00731.x |
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