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Cell Surface GRP78 as a Death Receptor and an Anticancer Drug Target
Cell surface GRP78 (csGRP78, glucose-regulated protein 78 kDa) is preferentially overexpressed in aggressive, metastatic, and chemo-resistant cancers. GRP78 is best studied as a chaperone protein in the lumen of endoplasmic reticulum (ER), facilitating folding and secretion of the newly synthesized...
Gardado en:
| Publicado en: | Cancers (Basel) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
MDPI
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6896222/ https://ncbi.nlm.nih.gov/pubmed/31766302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11111787 |
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