The chaperone GRP78 is a host auxiliary factor for SARS-CoV-2 and GRP78 depleting antibody blocks viral entry and infection

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the COVID-19 global pandemic, utilizes the host receptor angiotensin-converting enzyme 2 (ACE2) for viral entry. However, other host factors might also play important roles in SARS-CoV-2 infection, providing new...

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Vydáno v:J Biol Chem
Hlavní autoři: Carlos, Anthony J., Ha, Dat P., Yeh, Da-Wei, Van Krieken, Richard, Tseng, Chun-Chih, Zhang, Pu, Gill, Parkash, Machida, Keigo, Lee, Amy S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2021
Témata:
Accelerated Communication
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8102082/
https://ncbi.nlm.nih.gov/pubmed/33965375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100759
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