Design of a Short Thermally Stable α-Helix Embedded in a Macrocycle

Although helices play key roles in peptide–protein and protein–protein interactions, the helical conformation is generally unstable for short peptides (10–15 residues) in aqueous solution in the absence of their binding partners. Thus, stabilizing the helical conformation of peptides can lead to inc...

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Vydáno v:Chembiochem
Hlavní autoři: Wu, Haifan, Acharyya, Arusha, Wu, Yibing, Liu, Lijun, Jo, Hyunil, Gai, Feng, DeGrado, William F.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512792/
https://ncbi.nlm.nih.gov/pubmed/29417711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800026
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