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Residue specific vibrational echoes yield 3-dimensional structures of a transmembrane helix dimer
Two dimensional vibrational echo spectroscopy has previously been applied to structural determination of small peptides. Here we extend the technique to a more complex, biologically significant system: the homodimeric transmembrane dimer from the α-chain of the integrin αIIbβ3. We prepared micelle s...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3295544/ https://ncbi.nlm.nih.gov/pubmed/21636774 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1202997 |
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