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HILL COEFFICIENT ANALYSIS OF TRANSMEMBRANE HELIX DIMERIZATION

Here we employ the Hill equation, used broadly to characterize cooperativity in protein-ligand binding, to describe the dimerization of transmembrane (TM) helices in hydrophobic environments. The Hill analysis of wild-type FGFR3 TM domain dimerization gives a Hill coefficient of ~1 for lipid bilayer...

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Detaylı Bibliyografya
Asıl Yazarlar: Soong, Ricky, Merzlyakov, Mikhail, Hristova, Kalina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020080/
https://ncbi.nlm.nih.gov/pubmed/19603128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00232-009-9185-1
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