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Design of a Short Thermally Stable α-Helix Embedded in a Macrocycle

Although helices play key roles in peptide–protein and protein–protein interactions, the helical conformation is generally unstable for short peptides (10–15 residues) in aqueous solution in the absence of their binding partners. Thus, stabilizing the helical conformation of peptides can lead to inc...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Chembiochem
Main Authors: Wu, Haifan, Acharyya, Arusha, Wu, Yibing, Liu, Lijun, Jo, Hyunil, Gai, Feng, DeGrado, William F.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6512792/
https://ncbi.nlm.nih.gov/pubmed/29417711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800026
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