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Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast
DNA double-strand breaks (DSBs) are serious genomic insults that can lead to chromosomal rearrangements if repaired incorrectly. To gain insight into the nuclear mechanisms contributing to these rearrangements, we developed an assay in yeast to measure cis (same site) vs. trans (different site) repa...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2019
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6510992/ https://ncbi.nlm.nih.gov/pubmed/31019070 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818595116 |
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