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Frequency of DNA end joining in trans is not determined by the predamage spatial proximity of double-strand breaks in yeast

DNA double-strand breaks (DSBs) are serious genomic insults that can lead to chromosomal rearrangements if repaired incorrectly. To gain insight into the nuclear mechanisms contributing to these rearrangements, we developed an assay in yeast to measure cis (same site) vs. trans (different site) repa...

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Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Sunder, Sham, Wilson, Thomas E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2019
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6510992/
https://ncbi.nlm.nih.gov/pubmed/31019070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1818595116
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