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DNA polymerases δ and λ cooperate in repairing double-strand breaks by microhomology-mediated end-joining in Saccharomyces cerevisiae

Maintenance of genome stability is carried out by a suite of DNA repair pathways that ensure the repair of damaged DNA and faithful replication of the genome. Of particular importance are the repair pathways, which respond to DNA double-strand breaks (DSBs), and how the efficiency of repair is influ...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Meyer, Damon, Fu, Becky Xu Hua, Heyer, Wolf-Dietrich
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4687552/
https://ncbi.nlm.nih.gov/pubmed/26607450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1507833112
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