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Identification of Small Molecule Modulators of Diguanylate Cyclase by FRET-based High-Throughput-Screening
The bacterial second messenger cyclic diguanosine monophosphate (c-di-GMP) is a key regulator of cellular motility, the cell cycle, and biofilm formation with its resultant antibiotic tolerance, which may make chronic infections difficult to treat. Therefore, diguanylate cyclases, which regulate the...
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| Publicat a: | Chembiochem |
|---|---|
| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2018
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6509406/ https://ncbi.nlm.nih.gov/pubmed/30395379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.201800593 |
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