Identification of Small Molecules That Antagonize Diguanylate Cyclase Enzymes To Inhibit Biofilm Formation

Bacterial biofilm formation is responsible for numerous chronic infections, causing a severe health burden. Many of these infections cannot be resolved, as bacteria in biofilms are resistant to the host's immune defenses and antibiotic therapy. New strategies to treat biofilm-based infections a...

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Detalhes bibliográficos
Main Authors: Sambanthamoorthy, Karthik, Sloup, Rudolph E., Parashar, Vijay, Smith, Joshua M., Kim, Eric E., Semmelhack, Martin F., Neiditch, Matthew B., Waters, Christopher M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457405/
https://ncbi.nlm.nih.gov/pubmed/22850508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01396-12
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