Synthesis and Biological Evaluation of Bis-CNB-GABA, a Photoactivatable Neurotransmitter with Low Receptor Interference and Chemical Two-Photon Uncaging Properties

Por Shi, Diana D., Trigo, Federico F., Semmelhack, Martin F., Wang, Samuel S.-H.
Publicado em 2014

Broad Spectrum Pro-Quorum-Sensing Molecules as Inhibitors of Virulence in Vibrios

Por Ng, Wai-Leung, Perez, Lark, Cong, Jianping, Semmelhack, Martin F., Bassler, Bonnie L.
Publicado em 2012

The Quorum-Sensing Molecule Autoinducer 2 Regulates Motility and Flagellar Morphogenesis in Helicobacter pylori

Por Rader, Bethany A., Campagna, Shawn R., Semmelhack, Martin F., Bassler, Bonnie L., Guillemin, Karen
Publicado em 2007

Mechanism of Vibrio cholerae Autoinducer-1 Biosynthesis

Por Wei, Yunzhou, Perez, Lark J., Ng, Wai-Leung, Semmelhack, Martin F., Bassler, Bonnie L.
Publicado em 2011

The free and bound forms of Lpp occupy distinct subcellular locations in Escherichia coli

Por Cowles, Charles E., Li, Yongfeng, Semmelhack, Martin F., Cristea, Ileana M., Silhavy, Thomas J.
Publicado em 2011

Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae

Por Perez, Lark J., Karagounis, Theodora K., Hurley, Amanda, Bassler, Bonnie L., Semmelhack, Martin F.
Publicado em 2013

Caenorhabditis elegans Recognizes a Bacterial Quorum-sensing Signal Molecule through the AWC(ON) Neuron

Por Werner, Kristen M., Perez, Lark J., Ghosh, Rajarshi, Semmelhack, Martin F., Bassler, Bonnie L.
Publicado em 2014

Signal production and detection specificity in Vibrio CqsA/CqsS quorum-sensing systems

Por Ng, Wai-Leung, Perez, Lark J, Wei, Yunzhou, Kraml, Christina, Semmelhack, Martin F, Bassler, Bonnie L
Publicado em 2011

The Role of the CAI-1 Fatty Acid Tail in the Vibrio cholerae Quorum Sensing Response

Por Perez, Lark J., Ng, Wai-Leung, Marano, Paul, Brook, Karolina, Bassler, Bonnie L., Semmelhack, Martin F.
Publicado em 2012

A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

Por O’Loughlin, Colleen T., Miller, Laura C., Siryaporn, Albert, Drescher, Knut, Semmelhack, Martin F., Bassler, Bonnie L.
Publicado em 2013

Small molecule probes of the receptor binding site in the Vibrio cholerae CAI-1 quorum sensing circuit

Por Bolitho, Megan E., Perez, Lark J., Koch, Matthew J., Ng, Wai-Leung, Bassler, Bonnie L, Semmelhack, Martin F.
Publicado em 2011

Processing the Interspecies Quorum-sensing Signal Autoinducer-2 (AI-2): CHARACTERIZATION OF PHOSPHO-(S)-4,5-DIHYDROXY-2,3-PENTANEDIONE ISOMERIZATION BY LsrG PROTEIN

Por Marques, João C., Lamosa, Pedro, Russell, Caitlin, Ventura, Rita, Maycock, Christopher, Semmelhack, Martin F., Miller, Stephen T., Xavier, Karina B.
Publicado em 2011

Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa

Por Miller, Laura C., O’Loughlin, Colleen T., Zhang, Zinan, Siryaporn, Albert, Silpe, Justin E., Bassler, Bonnie L., Semmelhack, Martin F.
Publicado no J Med Chem (2015)

Identification of a Novel Benzimidazole That Inhibits Bacterial Biofilm Formation in a Broad-Spectrum Manner

Por Sambanthamoorthy, Karthik, Gokhale, Ankush A., Lao, Weiwei, Parashar, Vijay, Neiditch, Matthew B., Semmelhack, Martin F., Lee, Ilsoon, Waters, Christopher M.
Publicado em 2011

The structural basis for tight control of PP2A methylation and function by LCMT-1

Por Stanevich, Vitali, Jiang, Li, Satyshur, Kenneth A., Li, Yongfeng, Jeffrey, Philip D., Li, Zhu, Menden, Patrick, Semmelhack, Martin F., Xing, Yongna
Publicado em 2011

Probing bacterial transmembrane histidine kinase receptor–ligand interactions with natural and synthetic molecules

Por Ng, Wai-Leung, Wei, Yunzhou, Perez, Lark J., Cong, Jianping, Long, Tao, Koch, Matthew, Semmelhack, Martin F., Wingreen, Ned S., Bassler, Bonnie L.
Publicado em 2010

Identification of Small Molecules That Antagonize Diguanylate Cyclase Enzymes To Inhibit Biofilm Formation

Por Sambanthamoorthy, Karthik, Sloup, Rudolph E., Parashar, Vijay, Smith, Joshua M., Kim, Eric E., Semmelhack, Martin F., Neiditch, Matthew B., Waters, Christopher M.
Publicado em 2012

Structure, Regulation, and Inhibition of the Quorum-Sensing Signal Integrator LuxO

Por Boyaci, Hande, Shah, Tayyab, Hurley, Amanda, Kokona, Bashkim, Li, Zhijie, Ventocilla, Christian, Jeffrey, Philip D., Semmelhack, Martin F., Fairman, Robert, Bassler, Bonnie L., Hughson, Frederick M.
Publicado no PLoS Biol (2016)

Modulating Vibrio cholerae Quorum-Sensing-Controlled Communication Using Autoinducer-Loaded Nanoparticles

Por Lu, Hoang D., Spiegel, Alina C., Hurley, Amanda, Perez, Lark J., Maisel, Katharina, Ensign, Laura M., Hanes, Justin, Bassler, Bonnie L., Semmelhack, Martin F., Prud’homme, Robert K.
Publicado no Nano Lett (2015)

The Vibrio cholerae quorum-sensing autoinducer CAI-1: analysis of the biosynthetic enzyme CqsA

Por Kelly, Robert C., Bolitho, Megan E., Higgins, Douglas A., Lu, Wenyun, Ng, Wai-Leung, Jeffrey, Philip D., Rabinowitz, Joshua D., Semmelhack, Martin F., Hughson, Frederick M., Bassler, Bonnie L.
Publicado em 2009