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The structural basis for tight control of PP2A methylation and function by LCMT-1
Proper formation of protein phosphatase 2A (PP2A) holoenzymes is essential for fitness of all eukaryotic cells. Carboxyl-methylation of PP2A catalytic subunit plays a critical role in regulating holoenzyme assembly; methylation is catalyzed by PP2A-specific methyltransferase LCMT-1, an enzyme requir...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3060061/ https://ncbi.nlm.nih.gov/pubmed/21292165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.12.030 |
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