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Structural basis of PP2A activation by PTPA, an ATP-dependent activation chaperone
Proper activation of protein phosphatase 2A (PP2A) catalytic subunit is central for the complex PP2A regulation and is crucial for broad aspects of cellular function. The crystal structure of PP2A bound to PP2A phosphatase activator (PTPA) and ATPγS reveals that PTPA makes broad contacts with the st...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3915903/ https://ncbi.nlm.nih.gov/pubmed/24100351 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2013.138 |
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