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A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation

Quorum sensing is a chemical communication process that bacteria use to regulate collective behaviors. Disabling quorum-sensing circuits with small molecules has been proposed as a potential strategy to prevent bacterial pathogenicity. The human pathogen Pseudomonas aeruginosa uses quorum sensing to...

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Detalhes bibliográficos
Main Authors: O’Loughlin, Colleen T., Miller, Laura C., Siryaporn, Albert, Drescher, Knut, Semmelhack, Martin F., Bassler, Bonnie L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3816427/
https://ncbi.nlm.nih.gov/pubmed/24143808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316981110
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