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Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae

In the Vibrio cholerae pathogen, initiation of bacterial quorum sensing pathways serves to suppress virulence. We describe herein a potent and chemically stable small molecule agonist of V. cholerae quorum sensing, which was identified through rational drug design based on the native quorum sensing...

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Detalhes bibliográficos
Main Authors: Perez, Lark J., Karagounis, Theodora K., Hurley, Amanda, Bassler, Bonnie L., Semmelhack, Martin F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890260/
https://ncbi.nlm.nih.gov/pubmed/24436778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC52572D
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