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Highly Potent, Chemically Stable Quorum Sensing Agonists for Vibrio Cholerae

In the Vibrio cholerae pathogen, initiation of bacterial quorum sensing pathways serves to suppress virulence. We describe herein a potent and chemically stable small molecule agonist of V. cholerae quorum sensing, which was identified through rational drug design based on the native quorum sensing...

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書誌詳細
主要な著者: Perez, Lark J., Karagounis, Theodora K., Hurley, Amanda, Bassler, Bonnie L., Semmelhack, Martin F.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3890260/
https://ncbi.nlm.nih.gov/pubmed/24436778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C3SC52572D
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