Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2

Dna2 is an essential nuclease-helicase that acts in several distinct DNA metabolic pathways including DNA replication and recombination. To balance these functions and prevent unscheduled DNA degradation, Dna2 activities must be regulated. Here we show that Saccharomyces cerevisiae Dna2 function is...

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Bibliographic Details
Published in:Commun Biol
Main Authors: Ranjha, Lepakshi, Levikova, Maryna, Altmannova, Veronika, Krejci, Lumir, Cejka, Petr
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506525/
https://ncbi.nlm.nih.gov/pubmed/31098407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0428-0
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