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Nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity

Dna2 is a nuclease-helicase involved in several key pathways of eukaryotic DNA metabolism. The potent nuclease activity of Saccharomyces cerevisiae Dna2 was reported to be required for all its in vivo functions tested to date. In contrast, its helicase activity was shown to be weak, and its inactiva...

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Detalhes bibliográficos
Main Authors: Levikova, Maryna, Klaue, Daniel, Seidel, Ralf, Cejka, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670343/
https://ncbi.nlm.nih.gov/pubmed/23671118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300390110
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