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Nuclease activity of Saccharomyces cerevisiae Dna2 inhibits its potent DNA helicase activity

Dna2 is a nuclease-helicase involved in several key pathways of eukaryotic DNA metabolism. The potent nuclease activity of Saccharomyces cerevisiae Dna2 was reported to be required for all its in vivo functions tested to date. In contrast, its helicase activity was shown to be weak, and its inactiva...

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Hlavní autoři: Levikova, Maryna, Klaue, Daniel, Seidel, Ralf, Cejka, Petr
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3670343/
https://ncbi.nlm.nih.gov/pubmed/23671118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1300390110
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