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Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2

Dna2 is an essential nuclease-helicase that acts in several distinct DNA metabolic pathways including DNA replication and recombination. To balance these functions and prevent unscheduled DNA degradation, Dna2 activities must be regulated. Here we show that Saccharomyces cerevisiae Dna2 function is...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Ranjha, Lepakshi, Levikova, Maryna, Altmannova, Veronika, Krejci, Lumir, Cejka, Petr
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506525/
https://ncbi.nlm.nih.gov/pubmed/31098407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0428-0
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