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Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2

Dna2 is an essential nuclease-helicase that acts in several distinct DNA metabolic pathways including DNA replication and recombination. To balance these functions and prevent unscheduled DNA degradation, Dna2 activities must be regulated. Here we show that Saccharomyces cerevisiae Dna2 function is...

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Bibliografiske detaljer
Udgivet i:Commun Biol
Main Authors: Ranjha, Lepakshi, Levikova, Maryna, Altmannova, Veronika, Krejci, Lumir, Cejka, Petr
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506525/
https://ncbi.nlm.nih.gov/pubmed/31098407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0428-0
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