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Sumoylation regulates the stability and nuclease activity of Saccharomyces cerevisiae Dna2

Dna2 is an essential nuclease-helicase that acts in several distinct DNA metabolic pathways including DNA replication and recombination. To balance these functions and prevent unscheduled DNA degradation, Dna2 activities must be regulated. Here we show that Saccharomyces cerevisiae Dna2 function is...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Commun Biol
Hauptverfasser: Ranjha, Lepakshi, Levikova, Maryna, Altmannova, Veronika, Krejci, Lumir, Cejka, Petr
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506525/
https://ncbi.nlm.nih.gov/pubmed/31098407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0428-0
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