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Sumoylation of the Rad1 nuclease promotes DNA repair and regulates its DNA association
The Saccharomyces cerevisiae Rad1-Rad10 complex is a conserved, structure-specific endonuclease important for repairing multiple types of DNA lesions. Upon recruitment to lesion sites, Rad1-Rad10 removes damaged sequences, enabling subsequent gap filling and ligation. Acting at mid-steps of repair,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4041466/ https://ncbi.nlm.nih.gov/pubmed/24753409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku300 |
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