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Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation

The Srs2 DNA helicase of Saccharomyces cerevisiae affects recombination in multiple ways. Srs2 not only inhibits recombination at stalled replication forks but also promotes the synthesis-dependent strand annealing (SDSA) pathway of recombination. Both functions of Srs2 are regulated by sumoylation—...

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Библиографические подробности
Главные авторы: Kolesar, Peter, Sarangi, Prabha, Altmannova, Veronika, Zhao, Xiaolan, Krejci, Lumir
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2012
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439891/
https://ncbi.nlm.nih.gov/pubmed/22705796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks484
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