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Pro-recombination Role of Srs2 Protein Requires SUMO (Small Ubiquitin-like Modifier) but Is Independent of PCNA (Proliferating Cell Nuclear Antigen) Interaction

Srs2 plays many roles in DNA repair, the proper regulation and coordination of which is essential. Post-translational modification by small ubiquitin-like modifier (SUMO) is one such possible mechanism. Here, we investigate the role of SUMO in Srs2 regulation and show that the SUMO-interacting motif...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kolesar, Peter, Altmannova, Veronika, Silva, Sonia, Lisby, Michael, Krejci, Lumir
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4817187/
https://ncbi.nlm.nih.gov/pubmed/26861880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.685891
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