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Localization of recombination proteins and Srs2 reveals anti-recombinase function in vivo
Homologous recombination (HR), although an important DNA repair mechanism, is dangerous to the cell if improperly regulated. The Srs2 “anti-recombinase” restricts HR by disassembling the Rad51 nucleoprotein filament, an intermediate preceding the exchange of homologous DNA strands. Here, we cytologi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711611/ https://ncbi.nlm.nih.gov/pubmed/19506039 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200810055 |
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