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Unwinding of synthetic replication and recombination substrates by Srs2
The budding yeast Srs2 protein possesses 3′ to 5′ DNA helicase activity and channels untimely recombination to post-replication repair by removing Rad51 from ssDNA. However, it also promotes recombination via a synthesis-dependent strand-annealing pathway (SDSA). Furthermore, at the replication fork...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3484393/ https://ncbi.nlm.nih.gov/pubmed/22921573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2012.05.007 |
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