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Dual roles of the SUMO-interacting motif in the regulation of Srs2 sumoylation

The Srs2 DNA helicase of Saccharomyces cerevisiae affects recombination in multiple ways. Srs2 not only inhibits recombination at stalled replication forks but also promotes the synthesis-dependent strand annealing (SDSA) pathway of recombination. Both functions of Srs2 are regulated by sumoylation—...

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Détails bibliographiques
Auteurs principaux: Kolesar, Peter, Sarangi, Prabha, Altmannova, Veronika, Zhao, Xiaolan, Krejci, Lumir
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3439891/
https://ncbi.nlm.nih.gov/pubmed/22705796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks484
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