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Integrated computational and Drosophila cancer model platform captures previously unappreciated chemicals perturbing a kinase network
Drosophila provides an inexpensive and quantitative platform for measuring whole animal drug response. A complementary approach is virtual screening, where chemical libraries can be efficiently screened against protein target(s). Here, we present a unique discovery platform integrating structure-bas...
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| Publicado no: | PLoS Comput Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6506148/ https://ncbi.nlm.nih.gov/pubmed/31026276 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1006878 |
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