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“Nur77 links chronic antigen stimulation to B cell tolerance by restricting the survival of self-reactive B cells in the periphery”

Nur77 (Nr4a1) belongs to a small family of orphan nuclear receptors that are rapidly induced by B cell receptor (BCR) stimulation, yet little is known about its function in B cells. We have previously characterized a reporter of Nr4a1 transcription, Nur77-eGFP, in which GFP expression faithfully det...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Tan, Corey, Mueller, James L., Noviski, Mark, Huizar, John, Lau, Denise, Dubinin, Alexandra, Molofsky, Ari, Wilson, Patrick C., Zikherman, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504591/
https://ncbi.nlm.nih.gov/pubmed/30962292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1801565
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