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Self-reactivity on a spectrum: a sliding scale of peripheral B cell tolerance

Efficient mechanisms of central tolerance, including receptor editing and deletion, prevent highly self-reactive B cell receptors (BCRs) from populating the periphery. Despite this, modest self-reactivity persists in (and may even be actively selected into) the mature B cell repertoire. In this revi...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Immunol Rev
Päätekijät: Tan, Corey, Noviski, Mark, Huizar, John, Zikherman, Julie
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6935424/
https://ncbi.nlm.nih.gov/pubmed/31631352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12818
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