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Self-reactivity on a spectrum: a sliding scale of peripheral B cell tolerance
Efficient mechanisms of central tolerance, including receptor editing and deletion, prevent highly self-reactive B cell receptors (BCRs) from populating the periphery. Despite this, modest self-reactivity persists in (and may even be actively selected into) the mature B cell repertoire. In this revi...
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| Publicado no: | Immunol Rev |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6935424/ https://ncbi.nlm.nih.gov/pubmed/31631352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imr.12818 |
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