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“Control of autoreactive B cells by IgM and IgD B cell receptors: maintaining a fine balance”
A substantial fraction of mature naïve B cells recognize endogenous antigens, and this autoreactivity must be controlled to prevent autoantibody secretion. Selective downregulation of the IgM BCR on autoreactive B cells has long been appreciated, and recent findings illustrate how this might impose...
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| Publicado no: | Curr Opin Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6291015/ https://ncbi.nlm.nih.gov/pubmed/30292928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.09.015 |
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