Llwytho...

“Control of autoreactive B cells by IgM and IgD B cell receptors: maintaining a fine balance”

A substantial fraction of mature naïve B cells recognize endogenous antigens, and this autoreactivity must be controlled to prevent autoantibody secretion. Selective downregulation of the IgM BCR on autoreactive B cells has long been appreciated, and recent findings illustrate how this might impose...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Curr Opin Immunol
Prif Awduron: Noviski, Mark, Zikherman, Julie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6291015/
https://ncbi.nlm.nih.gov/pubmed/30292928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.09.015
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