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“Optimal development of mature B cells requires recognition of endogenous antigens”
It has long been appreciated that highly autoreactive BCRs are actively removed from the developing B cell repertoire by antigen-dependent receptor editing and deletion. However, there is persistent debate about whether mild autoreactivity is simply tolerated or positively selected into the mature B...
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| Publicado en: | J Immunol |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6668988/ https://ncbi.nlm.nih.gov/pubmed/31167773 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900175 |
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