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Total Synthesis of (–)-Xylogranatopyridine B via a Palladium-Catalyzed Oxidative Stannylation of Enones

We report a total synthesis of the pyridine-containing limonoid alkaloid (–)-xylogranatopyridine B in 11 steps from commercially available dihydrocarvone. The central pyridine ring was assembled by a late-stage fragment coupling approach employing a modified Liebeskind pyridine synthesis. One fragme...

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Bibliografiska uppgifter
I publikationen:J Am Chem Soc
Huvudupphovsmän: Schuppe, Alexander W., Huang, David, Chen, Yifeng, Newhouse, Timothy R.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499388/
https://ncbi.nlm.nih.gov/pubmed/29338207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.7b13189
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