Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

Developmental signal transduction pathways act diversely, with context-dependent roles across systems and disease types. Glioblastomas (GBMs), which are the poorest prognosis primary brain cancers, strongly resemble developmental systems, but these growth processes have not been exploited therapeuti...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Genes Dev
Prif Awduron: Rajakulendran, Nishani, Rowland, Katherine J., Selvadurai, Hayden J., Ahmadi, Moloud, Park, Nicole I., Naumenko, Sergey, Dolma, Sonam, Ward, Ryan J., So, Milly, Lee, Lilian, MacLeod, Graham, Pasiliao, Clarissa, Brandon, Caroline, Clarke, Ian D., Cusimano, Michael D., Bernstein, Mark, Batada, Nizar, Angers, Stephane, Dirks, Peter B.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Cold Spring Harbor Laboratory Press 2019
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499328/
https://ncbi.nlm.nih.gov/pubmed/30842215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.321968.118
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