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GENE-31. IDENTIFICATION OF CORE AND CONTEXT-SPECIFIC FITNESS GENES IN GLIOBLASTOMA STEM CELLS VIA GENOME-WIDE CRISPR-Cas9 SCREENS

Advances in the characterization of the genetic, epigenetic and transcriptomic landscapes of glioblastoma (GBM) tumor samples and primary cell lines have yielded considerable insight into tumor initiation and progression. A major finding from these studies is the high degree of inter- and intra-tumo...

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Dettagli Bibliografici
Pubblicato in:Neuro Oncol
Autori principali: MacLeod, Graham, Angers, Stephane, Dirks, Peter, Rajakulendran, Nishani, Ahmadi, Moloud, Bozek, Danielle, Luchman, Artee, Weiss, Sam
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847826/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.433
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