GENE-31. IDENTIFICATION OF CORE AND CONTEXT-SPECIFIC FITNESS GENES IN GLIOBLASTOMA STEM CELLS VIA GENOME-WIDE CRISPR-Cas9 SCREENS

Advances in the characterization of the genetic, epigenetic and transcriptomic landscapes of glioblastoma (GBM) tumor samples and primary cell lines have yielded considerable insight into tumor initiation and progression. A major finding from these studies is the high degree of inter- and intra-tumo...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: MacLeod, Graham, Angers, Stephane, Dirks, Peter, Rajakulendran, Nishani, Ahmadi, Moloud, Bozek, Danielle, Luchman, Artee, Weiss, Sam
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Genetics and Epigenetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6847826/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noz175.433
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