Wnt and Notch signaling govern self-renewal and differentiation in a subset of human glioblastoma stem cells

Developmental signal transduction pathways act diversely, with context-dependent roles across systems and disease types. Glioblastomas (GBMs), which are the poorest prognosis primary brain cancers, strongly resemble developmental systems, but these growth processes have not been exploited therapeuti...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Rajakulendran, Nishani, Rowland, Katherine J., Selvadurai, Hayden J., Ahmadi, Moloud, Park, Nicole I., Naumenko, Sergey, Dolma, Sonam, Ward, Ryan J., So, Milly, Lee, Lilian, MacLeod, Graham, Pasiliao, Clarissa, Brandon, Caroline, Clarke, Ian D., Cusimano, Michael D., Bernstein, Mark, Batada, Nizar, Angers, Stephane, Dirks, Peter B.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499328/
https://ncbi.nlm.nih.gov/pubmed/30842215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.321968.118
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