SC-05 DOPAMINE RECEPTOR ANTAGONISTS ARE SELECTIVE INHIBITORS OF GLIOBLASTOMA STEM CELLS THROUGH IMPAIRMENT OF AUTOPHAGY

Glioblastoma is an incurable cancer. The tumorigenic potential of glioblastoma resides within cells with a stem cell phenotype called glioblastoma stem cells. In order to identify novel glioblastoma drugs, we interrogated a library of 680 neuromodulatory compounds for their activity on glioblastoma...

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Publicado en:Neuro Oncol
Main Authors: Dolma, Sonam, So, Milly, Voisin, Veronique, Zhu, Xueming, Head, Renee, Clarke, Ian, Bader, Gary, Tyers, Michael, Dirks, Peter
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218600/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou275.5
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