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Depletion of somatic mutations in splicing-associated sequences in cancer genomes
BACKGROUND: An important goal of cancer genomics is to identify systematically cancer-causing mutations. A common approach is to identify sites with high ratios of non-synonymous to synonymous mutations; however, if synonymous mutations are under purifying selection, this methodology leads to identi...
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| 出版年: | Genome Biol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5678748/ https://ncbi.nlm.nih.gov/pubmed/29115978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-017-1337-5 |
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