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Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

BACKGROUND: Driven by high throughput next generation sequencing technologies and the pressing need to decipher cancer genomes, computational approaches for detecting somatic single nucleotide variants (sSNVs) have undergone dramatic improvements during the past 2 years. The recently developed tools...

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Hlavní autoři: Wang, Qingguo, Jia, Peilin, Li, Fei, Chen, Haiquan, Ji, Hongbin, Hucks, Donald, Dahlman, Kimberly Brown, Pao, William, Zhao, Zhongming
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971343/
https://ncbi.nlm.nih.gov/pubmed/24112718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm495
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