Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

BACKGROUND: Driven by high throughput next generation sequencing technologies and the pressing need to decipher cancer genomes, computational approaches for detecting somatic single nucleotide variants (sSNVs) have undergone dramatic improvements during the past 2 years. The recently developed tools...

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Detalhes bibliográficos
Main Authors: Wang, Qingguo, Jia, Peilin, Li, Fei, Chen, Haiquan, Ji, Hongbin, Hucks, Donald, Dahlman, Kimberly Brown, Pao, William, Zhao, Zhongming
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971343/
https://ncbi.nlm.nih.gov/pubmed/24112718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm495
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