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Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

BACKGROUND: Driven by high throughput next generation sequencing technologies and the pressing need to decipher cancer genomes, computational approaches for detecting somatic single nucleotide variants (sSNVs) have undergone dramatic improvements during the past 2 years. The recently developed tools...

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Dettagli Bibliografici
Autori principali: Wang, Qingguo, Jia, Peilin, Li, Fei, Chen, Haiquan, Ji, Hongbin, Hucks, Donald, Dahlman, Kimberly Brown, Pao, William, Zhao, Zhongming
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971343/
https://ncbi.nlm.nih.gov/pubmed/24112718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm495
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