Detecting somatic point mutations in cancer genome sequencing data: a comparison of mutation callers

BACKGROUND: Driven by high throughput next generation sequencing technologies and the pressing need to decipher cancer genomes, computational approaches for detecting somatic single nucleotide variants (sSNVs) have undergone dramatic improvements during the past 2 years. The recently developed tools...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Wang, Qingguo, Jia, Peilin, Li, Fei, Chen, Haiquan, Ji, Hongbin, Hucks, Donald, Dahlman, Kimberly Brown, Pao, William, Zhao, Zhongming
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2013
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971343/
https://ncbi.nlm.nih.gov/pubmed/24112718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm495
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