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The Role of Structural Polymorphism in Driving the Mechanical Performance of the Alzheimer's Beta Amyloid Fibrils
Alzheimer's Disease (AD) is related with the abnormal aggregation of amyloid β-peptides Aβ(1−40) and Aβ(1−42), the latter having a polymorphic character which gives rise to U- or S-shaped fibrils. Elucidating the role played by the nanoscale-material architecture on the amyloid fibril stability...
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| Publicado no: | Front Bioeng Biotechnol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6499180/ https://ncbi.nlm.nih.gov/pubmed/31106199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fbioe.2019.00083 |
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