טוען...
Josephin Domain Structural Conformations Explored by Metadynamics in Essential Coordinates
The Josephin Domain (JD), i.e. the N-terminal domain of Ataxin 3 (At3) protein, is an interesting example of competition between physiological function and aggregation risk. In fact, the fibrillogenesis of Ataxin 3, responsible for the spinocerebbellar ataxia 3, is strictly related to the JD thermod...
שמור ב:
| הוצא לאור ב: | PLoS Comput Biol |
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| Main Authors: | , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4706304/ https://ncbi.nlm.nih.gov/pubmed/26745628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004699 |
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