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Conformational Dynamics and Stability of U-Shaped and S-Shaped Amyloid β Assemblies
Alzheimer’s disease is the most fatal neurodegenerative disorder characterized by the aggregation and deposition of Amyloid β (Aβ) oligomers in the brain of patients. Two principal variants of Aβ exist in humans: Aβ(1–40) and Aβ(1–42). The former is the most abundant in the plaques, while the latter...
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Udgivet i: | Int J Mol Sci |
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Main Authors: | , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
MDPI
2018
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5855793/ https://ncbi.nlm.nih.gov/pubmed/29443891 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020571 |
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