Proximal tubule transferrin uptake is modulated by cellular iron and mediated by apical membrane megalin–cubilin complex and transferrin receptor 1

Receptor-mediated endocytosis is responsible for reabsorption of transferrin (Tf) in renal proximal tubules (PTs). Although the role of the megalin–cubilin receptor complex (MCRC) in this process is unequivocal, modalities independent of this complex are evident but as yet undefined. Here, using imm...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Smith, Craig P., Lee, Wing-Kee, Haley, Matthew, Poulsen, Søren B., Thévenod, Frank, Fenton, Robert A.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2019
Konular:
Membrane Biology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6497946/
https://ncbi.nlm.nih.gov/pubmed/30833328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.006390
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