Megalin-dependent cubilin-mediated endocytosis is a major pathway for the apical uptake of transferrin in polarized epithelia

Cubilin is a 460-kDa protein functioning as an endocytic receptor for intrinsic factor vitamin B(12) complex in the intestine and as a receptor for apolipoprotein A1 and albumin reabsorption in the kidney proximal tubules and the yolk sac. In the present study, we report the identification of cubili...

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Main Authors: Kozyraki, Renata, Fyfe, John, Verroust, Pierre J., Jacobsen, Christian, Dautry-Varsat, Alice, Gburek, Jakub, Willnow, Thomas E., Christensen, Erik Ilsø, Moestrup, Søren K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The National Academy of Sciences 2001
Ábhair:
Biological Sciences
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC60081/
https://ncbi.nlm.nih.gov/pubmed/11606717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.211291398
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